Trilinolein

AKA: 537-40-6, Glycerol trilinoleate, EFADERMA-F, 2, 3-bis[[(9Z, 12Z)-octadeca-9, 12-dienoyl]oxy]propyl (9Z, 12-dienoate, (Z, Z)-9, 12-Octadecadienoic acid, 1, 3-propanetriyl ester, Trilinoelaidate, Trilinoleic glycerol
Synthetic
Skin Conditioner
Clean
OriginSynthesized from linoleic acid or linolenic acid, which are polyunsaturated fatty acids from plant oils. Produced through esterification of these fatty acids with glycerol under catalytic conditions.
Propane-1,2,3-triyl tris[(9Z,12Z)-octadeca-9,12-dienoate]
Formula
C57H98O6
Mol. Weight
879.40
CAS #
537-40-6
Form
Powder
State
Solid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Viscosity Controlling
Locks in moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
Leave-on0.0048–0.017%
Rinse-off0.00048–0.0048%
0%50%100%
CIR reported use · 2017 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR