Trimethyl Pentanyl Diisobutyrate

AKA: 6846-50-0, 2, 4-Trimethyl-1, 3-pentanediol diisobutyrate, Kodaflex txib, TXIB, Propanoic acid, 2-dimethyl-1-(1-methylethyl)-1, 3-propanediyl ester, 4-Trimethylpentanediol-1, 3-diisobutyrate, Isobutyric acid, 1-isopropyl-2, 2-dimethyltrimethylene ester
Synthetic
Clean
OriginDerived from branched aliphatic alcohols and isobutyric acid, both petroleum-based chemical feedstocks. Synthesized through esterification reaction between the alcohol and acid using catalytic conditions.
1-Isopropyl-2,2-dimethyltrimethylene diisobutyrate
Formula
C16H30O4
Mol. Weight
286.41
CAS #
6846-50-0
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
Functions
Plasticiser
Antioxidant
Anti-Inflammatory
Moisturizing
Adds flexibility
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 735)
Not an Eye Irritant
1 study / 1 not irritating (CIR 735)
Mixed Skin Irritation Results
2 studies / 1 mixed / 1 not irritating / reactions mild (CIR 735)
Concentration Guide
Leave-on0.1–9.8%
Rinse-off2%
0%50%100%
CIR reported use · report published 2017
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR