Trimethylbenzoyl Diphenylphosphine Oxide
molecular structure · PubChem
AKA: 75980-60-8, Diphenyl(2, 4, 6-trimethylbenzoyl)phosphine oxide, 2, 6-trimethylbenzoyl diphenylphosphine oxide, CHIVACURE TPO, DOUBLECURE TPO
Synthetic
Skin Conditioner
Not Clean
diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide
Solubility Water solubility: 3.3 mg/L at 20 °C (OECD Guideline 105, Flask method) and 11.9 mg/L at 20 °C (OECD Guideline 105, Column elution). Readily soluble in dichloromethane, acetone, n-butylacetate; soluble in styrene and in other monomers.
Formula
C22H21O2P
Mol. Weight
348.40
CAS #
75980-60-8
Form
Powder
State
NKRA; Pellets or Large Crystals, Liquid; Liquid; Dry Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A synthetic photoinitiator developed for cosmetic and coating applications. Created to enable UV-curing in modern cosmetic formulations such as nail polish and gel products.
EWG
6
CIR
Insufficient data
Pregnancy
Caution
CIR Safety Findings
all-shades-safe
Concentration Guide
5.0%
0%7%
Reg. Limit
EU/SCCS limit: 5% in cosmetic products. Opinion: SCCS/1528/14
Regulatory Agencies
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR