Trimethylsiloxysilicate

Trimethylsiloxysilicate 1
molecular structure · PubChem CID 87094716
Synthetic
Emollient
Skin Conditioner
Clean
OriginDerived from silicone chemistry, specifically the organosiloxane compound family synthesized from silicon-based precursors. Produced through condensation polymerization of siloxane monomers and dimethicone polymers under controlled catalytic conditions.
Silica, reaction products with trimethylsilane
Formula
C6H18O5Si3
Mol. Weight
254.46
CAS #
68611-44-9; 1015787-46-8; 211811-62-0; 68909-20-6; 112153-70-5; 112153-71-6; 1123693-37-7; 70536-25-3; 371755-66-7; 1158846-14-0
Form
Powder
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Antifoaming
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Mixed Skin Irritation Results
5 studies / 2 irritating / 3 not irritating / reactions slight (CIR 584)
Mixed Eye Irritation Results
5 studies / 1 irritating / 4 not irritating (CIR 584)
Mixed Sensitization Results
3 studies / 1 sensitizing / 2 not sensitizing / reactions weak (CIR 584)
Concentration Guide
Leave-on0.0001–30%
Rinse-off0.002–5%
0%50%100%
CIR reported use · 2010 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR