Trimethylsiloxysilicate

Synthetic
Emollient
Skin Conditioner
Silicone
Clean
Silica, reaction products with trimethylsilane
Formula
C6H18O5Si3
Mol. Weight
254.46
CAS #
68611-44-9; 1015787-46-8; 211811-62-0; 68909-20-6; 112153-70-5; 112153-71-6; 1123693-37-7; 70536-25-3; 371755-66-7; 1158846-14-0
Form
Powder
Functions
Antifoaming
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Developed as a silicone-based polymer in the late 20th century. Used in cosmetics as a mattifying agent and skin-feel enhancer, particularly in powders, foundations, and silicone-based skincare products.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Potential Sensitizer
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR