Trioleyl Phosphate

AKA: Hostaphat KO 300, 3305-68-8, NIKKOL TOP-0, 9-Octadecen-1-ol, Phosphate (3:1), 9-OCTADECEN-1-OL, PHOSPHATE (3:1), 1''-PHOSPHATE

Synthetic

Emollient

Skin Conditioner

Not Clean

The CIR Expert Panel concluded the following 28 alkyl phosphates are safe in the present practices of use and concentration in cosmetics when formulated to be non-irritating...Trioleyl Phosphate...

Effective at 2.11%

Formula

C54H105O4P

Mol. Weight

849.40

CAS #

3305-68-8

Form

Powder

Functions

Plasticiser

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Emollient

Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.

Locks In Moisture

Traditional Use

A modern synthetic ester developed as an emollient and conditioning agent for cosmetics. Designed to improve skin feel and product stability in contemporary formulations.

EWG

CIR

Safe as used

Pregnancy

Yes

CIR Safety Findings

Not a Sensitizer

medical-approval

all-shades-safe

Concentration Guide

0.02%

4.2%

0%6%

Reported use

CIR reported use: 0.02-4.2

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Skin Types

●all-skin-types

Best For

Dryness

Pregnancy & Breastfeeding Safe

Yes

The paper trail

🔬Peer-reviewed1 paper →

⚖️Regulatory1 listing →

🛡️Safety-assessed1 review →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

Verified Jun 2026

Data: PubChem · CosIng · EWG · CIR