Trisodium Ethylenediamine Disuccinate

Trisodium Ethylenediamine Disuccinate 1
molecular structure · PubChem
AKA: 178949-82-1, L-Aspartic acid, Trisodium salt, NATRLQUEST E30, NATRLQUEST E 30, ENVIOMET C140, Trisodiumethylenediamine disuccinate, Sodium salt (1:3), TRISODIUM-ETHYLENEDIAMINEDISUCCINATE, (S, S)-ETHYLENEDIAMINE DISUCCINIC ACID TRISODIUM SALT
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Synthetic
Chelating Agent
Clean
OriginSynthesized from ethylenediamine and succinic acid, both organic compounds derived from petrochemical or bio-based sources. Produced through condensation reaction between ethylenediamine and succinic acid, followed by neutralization with sodium hydroxide.
L-Aspartic acid, N,N'-1,2-ethanediylbis-, trisodium salt
Formula
C10H13N2Na3O8
Mol. Weight
358.19
CAS #
20846-91-7, 178949-82-1
Form
Liquid
State
Liquid
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Antioxidant
Boosts Collagen
Binds metal ions
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
3 studies / 3 not irritating (CIR 848)
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 848)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions slight (CIR 848)
Concentration Guide
Leave-on0.01–0.64%
Rinse-off0.0039–0.51%
0%50%100%
CIR reported use · report published 2023
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR