Trisodium Fructose Diphosphate

AKA: Fosfructose trisodium, 81028-91-3, Fosfructose trisodium [USAN], FOSFRUCTOSE TRISODIUM [MART.], FOSFRUCTOSE TRISODIUM [WHO-DD], D-Fructose 1, 6-bis(dihydrogen phosphate), Trisodium salt, Octahydrate, Trisodium fructose 1, 6-diphosphate octahydrate
Synthetic
Antioxidant
Chelating Agent
Not Clean
D-Fructose, 1,6-bis(dihydrogen phosphate), trisodium salt, octahydrate
Formula
C6H27Na3O20P2
Mol. Weight
550.18
CAS #
81028-91-3
Form
Powder
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Neutralizes Free Radicals
Traditional Use
A modern synthetic ingredient developed as a skin conditioning and antioxidant agent in contemporary cosmetic formulations. No significant traditional or historical use.
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR