Trisodium Glycyrrhizate

Trisodium Glycyrrhizate 1
molecular structure · PubChem CID 24838409
AKA: Trisodium glycyrrhizinate, Trisodium glycyrrhizin, CCRIS 9136, ORISTAR TSG, GLYCYRRHIZINATE, TRISODIUM GLYCYRRHIZATE VINYALS, Alpha-D-Glucopyranosiduronic acid, Trisodium salt
Synthetic
Skin Conditioner
Clean
OriginDerived from glycyrrhizin, the active compound extracted from licorice root (Glycyrrhiza glabra). Synthesized through saponification and neutralization of glycyrrhizin with sodium hydroxide.
20beta-Carboxy-11-oxo-30-nor-olean-12-en-3beta-yl-2-O-beta-D-glucopyranuronosyl-alfa-D-glucopyranosiduronic acid, trisodium salt; Trisodium glycyrrhizate
Formula
C42H59Na3O16
Mol. Weight
888.90
CAS #
71277-78-6
Form
Powder
Skin Types
●all-skin-types
Best For
Redness
Pregnancy & Breastfeeding Safe
Caution
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Brightens uneven skin tone
Evens pigmentation
Quells irritation
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not Phototoxic (CIR Panel on the ingredient group)
CIR Panel statement covering this group of ingredients; not tested individually (CIR 349)
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR