Trisodium Inositol Triphosphate

AKA: IP3

Synthetic

Skin Conditioner

Clean

OriginSynthesized from inositol and phosphoric acid through chemical esterification and neutralization with sodium compounds. Produced via multi-step organic synthesis involving phosphorylation of inositol followed by sodium salt formation.

Trisodium Inositol Triphosphate

CAS #

34367-89-0; 83-86-3; 59-56-3

Form

Powder

Skin Types

●all-skin-types

Best For

General

Pregnancy & Breastfeeding Safe

Yes

Functions

Skin Conditioning

A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.

Locks in moisture

The paper trail

🔬Peer-reviewednone on file

⚖️Regulatory1 listing →

🛡️Safety-assessed3 reviews →

Counts, not a verdict. A listing isn't a study. The trail, you decide.

EWG

CIR

Safe as used

Pregnancy

Yes

Concentration Guide

CIR lists it as not reported to be in use.

CIR · report published 2024

Regulatory Status

USA✔ permitted

EU⚠ restricted

JAPAN⚠ restricted

CANADA⚠ restricted

Regulatory Agencies

EWG CIR FDA EU COSING Health Canada

Verified Jun 2026

Data: CosIng · EWG · CIR