Tris(Tetramethylhydroxypiperidinol) Citrate

AKA: 220410-74-2, 4-Piperidinol, 2-hydroxy-1, 2, 3-propanetricarboxylate (3:1) (salt), 3-propanetricarboxylate (3:1)
Synthetic
Sunscreen Filter
Clean
OriginSynthesized from piperidine derivatives and citric acid through multi-step organic synthesis reactions. Produced by esterification and condensation of methylhydroxypiperidinol compounds with citrate salts.
4-Piperidinol, 1-Hydroxy-2,2,6,6-Tetramethyl -, 2-Hydroxy-1,2,3-Propanetricarboxylate (3:1) (salt)
Formula
C33H65N3O13
Mol. Weight
711.90
CAS #
220410-74-2
Form
Liquid
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
Functions
Uv Absorber
Blocks or absorbs UV rays to protect your skin from sun damage, dark spots, and premature aging.
Shields from UV damage
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Skin Irritant
1 study / 1 not irritating (CIR 812)
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 812)
Not an Eye Irritant
1 study / 1 not irritating (CIR 812)
Concentration Guide
Leave-on0.0001–0.05%
Rinse-off0.005–0.05%
0%50%100%
CIR reported use · report published 2025
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR
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