Ubiquinol

AKA: Reduced coenzyme Q10, Ubiquinone hydroquinone, 1, 4-Benzenediol, 2-[(2E, 6E, 10E, 14E, 18E, 22E, 26E, 30E, 34E)-3, 7, 11, 15, 19, 23, 27, 31, 35, 39-decamethyltetraconta-2, 6, 10, 14, 18, 22, 26, 30, 34, 38-decaenyl]-5, 6-dimethoxy-3-methylbenzene-1, 4-diol, CHEBI:17976, CoQH2, Reduced ubiquinone
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Synthetic
Antioxidant
Humectant
Skin Conditioner
Barrier Support
Clean
OriginUbiquinol is a reduced form of coenzyme Q10, belonging to the quinone chemical family synthesized through organic chemistry. It is produced through catalytic hydrogenation of ubiquinone, converting the oxidized form to its reduced state.
Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects of vitamin E by regenerating the vitamin from the tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There are varying concentrations of ubiquinol in foods, OTC products and dietary supplement products.
Formula
C59H92O4
Mol. Weight
865.40
CAS #
56275-39-9
Form
Liquid
State
Solid
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Nourishes & Protects
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
Concentration Guide
CIR's newest survey reports no concentration of use.
CIR · 2018 survey
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR