Ubiquinol

Ubiquinol molecular structure
molecular structure · PubChem
AKA: Reduced coenzyme Q10, Ubiquinone hydroquinone, 1, 4-Benzenediol, 2-[(2E, 6E, 10E, 14E, 18E, 22E, 26E, 30E, 34E)-3, 7, 11, 15, 19, 23, 27, 31, 35, 39-decamethyltetraconta-2, 6, 10, 14, 18, 22, 26, 30, 34, 38-decaenyl]-5, 6-dimethoxy-3-methylbenzene-1, 4-diol, CHEBI:17976, CoQH2, Reduced ubiquinone
Synthetic
Antioxidant
Humectant
Skin Conditioner
Barrier Support
Clean
Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects of vitamin E by regenerating the vitamin from the tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There are varying concentrations of ubiquinol in foods, OTC products and dietary supplement products.
Formula
C59H92O4
Mol. Weight
865.40
CAS #
56275-39-9
Form
Liquid
State
Solid
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Protecting
Helps rebuild and strengthen your skin barrier — the invisible shield that keeps moisture in and irritants out. Essential after over-exfoliating or harsh weather.
Nourishes & Protects
Locks In Moisture
Traditional Use
The reduced form of Coenzyme Q10, discovered in 1957. Ubiquinol emerged in skincare in the 1990s-2000s as an antioxidant based on research showing it supports cellular energy production and may reduce the appearance of wrinkles, with no traditional use history.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR