Vitis vinifera (Grape) leaf extract

AKA: Wine grape, Grape Leaf Extract
Plant-Derived
Skin Conditioner
Extract
Clean
Vitis Vinifera (Grape) Leaf Extract is a cosmetic ingredient used as skin conditioning. Rated low hazard by EWG. Assessed as safe by the CIR.
Family
Vitaceae (Grapevine family)
Plant Part
Leaf
Lifeform
Liana
Climate
Temperate
CAS #
85594-37-2 / 84929-27-1
Form
Liquid
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Anti-Aging Benefits
Antioxidant Protection
Reduces Inflammation
Softens & Smooths
Traditional Use
Grape leaves have been used in traditional Mediterranean and Middle Eastern medicine for circulation and skin health. The extract is a modern cosmetic application of these historical uses, valued for its proanthocyanidin and polyphenol content.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types, gentle
Best For
Dullness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper
⚖️Regulatory1 listing
🛡️Safety-assessed2 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: Kew POWO · CosIng · EWG · CIR