Vitis vinifera (Grape) seed
AKA: Wine grape, Grape Seed
Plant-Derived
Skin Conditioner
Clean
Vitis Vinifera (Grape) Seed is a cosmetic ingredient used as skin conditioning. Rated low hazard by EWG. Assessed as safe by the CIR.
Effective at 1.5%
Family
Vitaceae (Grape family)
Plant Part
Seed
Lifeform
Liana
Climate
Temperate
CAS #
85594-37-2 / 84929-27-1
Form
Powder
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Conditions Skin
Antioxidant Protection
Reduces Inflammation
Fights Bacteria
Softens & Smooths
Traditional Use
Grape seeds have been valued since ancient times in Mediterranean cultures for their astringent tannins, used in traditional skincare and for general wellness.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
0.01%
3.0%
0%4%
Reported use
CIR reported use: 0.01-3 | 0.05-0.08
Regulatory Agencies
Skin Types
●all-skin-types
Best For
Dullness
Pregnancy & Breastfeeding Safe
Yes
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: Kew POWO · CosIng · EWG · CIR