Zinc PCA

Zinc PCA molecular structure
molecular structure · PubChem
AKA: Zinc pidolate, Zinc pyroglutamate, Proline, Zinc salt (2:1), ZINC PYRROLIDONE CARBOXYLATE, ZINC L-PYROGLUTAMATE
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Synthetic
Humectant
Skin Conditioner
Not Clean
OriginSynthesized from zinc salts and pyrrolidone carboxylic acid (PCA), a naturally occurring amino acid derivative. Produced through chemical reaction between zinc compounds and PCA to form the zinc complex salt.
Proline, 5-oxo-, zinc salt
Formula
C10H12N2O6Zn
Mol. Weight
321.60
CAS #
68107-75-5, 15454-75-8
Form
Powder
Skin Types
●all-skin-types
Best For
Acne
Pregnancy & Breastfeeding Safe
Yes
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed1 review →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
4
CIR
Safe
Pregnancy
Yes
Concentration Guide
0%50%100%
Reg. limit 1%
EU regulatory limit: 1%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 24.
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR