Zinc Sulfate

AKA: Zinc sulphate, 7733-02-0, Zinc sulfate anhydrous, Zincate, White vitriol, Zinc(II) sulfate, Zinc sulfate (1:1), Medizinc, Solvezinc
Synthetic
Preservative
Astringent
Not Clean
OriginZinc sulfate belongs to the metal sulfate chemical family, synthesized from zinc metal or zinc oxide compounds. Produced by reacting zinc with sulfuric acid or by roasting zinc-containing ores followed by acid leaching.
Zinc sulfate is used as a malting/fermenting aid and as a nutrient supplement Zinc sulfate (ZnSO4) is a colorless crystalline, water-soluble chemical compound. The hydrated form, ZnSO4*7H2O, the mineral goslarite, was historically known as white vitriol and can be prepared by reacting zinc with aqueous sulfuric acid. It may also be prepared by adding solid zinc to a copper(II) sulfate solution.<br /> Zinc sulfate has been shown to exhibit antibiotic and anti-spectic functions (A7766, A7767).<br /> Zinc sulfate belongs to the family of Transition Metal Sulfates. These are inorganic compounds in which the largest oxoanion is sulfate, and in which the heaviest atom not in an oxoanion is a transition metal.
Solubility Solubility: 54.480 lb/100 lb water /Heptahydrate/
Formula
O4SZn
Mol. Weight
161.40
CAS #
7446-19-7, 7733-02-0, 7746-20-0
Form
Powder
State
Anhydrous zinc sulfate is a colorless crystalline solid. Zinc sulfate is also obtained as a hexahydrate, ZnSO4.6H2O, and as a heptahydrate ZnSO4.7H2O. All forms are soluble in water. All are noncombus
Skin Types
●all-skin-types
Best For
Acne
Pregnancy & Breastfeeding Safe
Yes
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Antiplaque
Astringent
Tightens and contracts skin tissue, temporarily shrinking pores and reducing oiliness. That "clean, tight" feeling after toner.
Oral Care
Controls excess oil
Fights acne
Causing bacteria
Minimizes pores
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
5
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Mixed Skin Irritation Results
3 studies / 2 irritating / 1 not irritating / reactions slight (CIR 755)
Mixed Sensitization Results
2 studies / 1 mixed / 1 not sensitizing (CIR 755)
Eye Irritant in Testing
1 study / 1 irritating / reactions severe (CIR 755)
Dermal Absorption 0.3–1.6%
pig skin / in vitro / flow-through diffusion cells / 40 mg/mL Zinc Sulfate (monohydrate) in water / applied 8 h without occlusion (CIR 755)
Concentration Guide
Leave-on0.0001–1%
Rinse-off0.0003–0.15%
0%50%100%
CIR reported use · 2016 survey
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR