Final Report: Safety Assessment o…as Used in Cosmetics

🛡️ Safety-assessed

Final Report: Safety Assessment of Polysilsesquioxanes as Used in Cosmetics

Cosmetic Ingredient Review (CIR) Expert Panel

International Journal of Toxicology

Findings

Safety assessment of 18 ingredients used in cosmetics

Design

Review

Evidence

Strong

Journal

International Journal of Toxicology

Ingredients studied

Acryloyloxypropyl Polysilsesquioxane →C26-28 Alkyldimethylsilyl Polypropylsilsesquioxane →C30-45 Alkyldimethylsilyl Polypropylsilsesquioxane →Dimethicone/Silsesquioxane Copolymer →Dimethiconol/Caprylylsilsesquioxane/Silicate Crosspolymer →Ethyl Polysilsesquioxane →Hydrogen Dimethicone/Octyl Silsesquioxane Copolymer →Isobutyl Polysilsesquioxane →Isobutyl/Methoxy PEG-10 Polysilsesquioxane →Methacryloyloxypropyl Polysilsesquioxane →Methoxy PEG-10 Polysilsesquioxane →Polycaprylylsilsesquioxane →Polydimethylsiloxy PEG/PPG-24/19 Butyl Ether Silsesquioxane →Polydimethylsiloxy PPG-13 Butyl Ether Silsesquioxane →Polymethylsilsesquioxane →Polymethylsilsesquioxane/Trimethylsiloxysilicate →Polypropylsilsesquioxane →Trimethylpentyl Polysilsesquioxane →