Ceramide NG
AKA “Ceramide 2, n-stearoyl dihydrosphingosine, Ceramide NS, Ceramide 2 pure, C04977SRJ5, (2S, 3R)-2-(Octadecanoylamino)octadecane-1, 3-diol, 1-stearoyl-C18-sphingosine, palmitoyl-c16-dihydrosphingosine, CERAMIDE TIC-001
Synthetic
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Ingredient Facts
Ceramide ng
AKA: Ceramide 2, N-stearoyl dihydrosphingosine, Ceramide NS, Ceramide 2 pure, C04977SRJ5, (2S, 3R)-2-(Octadecanoylamino)octadecane-1, 3-diol, 1-stearoyl-C18-sphingosine, Palmitoyl-c16-dihydrosphingosine, CERAMIDE TIC-001
Synthetic · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Ceramide
Synthetic
Clean
N-octodecanoylsphinganine is a dihydroceramide in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It has a role as a mouse metabolite. It is a N-stearoyl-sphingoid base and a N-acylsphinganine. It is functionally related to an octadecanoic acid.
Formula
C36H73NO3
Mol. Weight
568.00
CAS #
2304-80-5
Form
Liquid
State
Solid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning Miscellaneous
Improves skin feel
Traditional Use
A synthetic humectant and emollient developed for cosmetic use in the late 20th century. Created to improve hydration and skin conditioning without natural historical precedent.
Skin Types
all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
The New Tendency Complete Set
Nécessaire
 →
body cleansing bar
Cocokind
 →
calm & clarify duo
Cocokind
 →
ceramide hydration duo
Cocokind
 →
Fleuressence
Goldfaden MD
 →
Glow Getters Trio
Goldfaden MD
 →
The Hand Cream + The Tube Key
Nécessaire
 →
Skin Rewind Complexion Stick
ILIA Beauty
 →
milky-soft face and body cleanser
Cocokind
 →
Blurring Blot Balm & Primer
MOB Beauty
 →
Blurring Ceramide Cream Foundation
MOB Beauty
 →
Hyaluronic Highlight Balm
MOB Beauty
 →
Hyaluronic Highlight Balm Last Call
MOB Beauty
 →
Suspended Sparkle Balm
MOB Beauty
 →
Suspended Sparkle Balm Last Call
MOB Beauty
 →
The New Tendency Duo
Nécessaire
 →
peptide fine line eye gel
Cocokind
 →
retinol face + body duo
Cocokind
 →
rise + shine trio
Cocokind
 →
Brightening Bubbling Cleanser
Alpyn Beauty
 →
Line-Filling Eye Balm
Alpyn Beauty
 →
Melt Moisturizer
Alpyn Beauty
 →
The Radiance Ritual
Alpyn Beauty
 →
DreamBeam SPF 40 PA++++
Kosas
 →
Plump + Juicy Cleansing Oil
Kosas
 →
Wet Stick
Kosas
 →
The Hand Duo
Nécessaire
 →
The Hand-Lip Moisture Duo
Nécessaire
 →
The Lip Balm Duo
Nécessaire
 →
We're Expecting (a Glow) Set
Goldfaden MD
 →
youthful duo
Cocokind
 →
Addendum to the Final Report on the Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol (JEPT 4(4) 47-61 1980)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report of the Safety Assessment for 2-Bromo-2-Nitropropane-1,3-Diol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Revised Tentative Report: Amended Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
2-Bromo-2-Nitropropane-1,3-Diol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide 2
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide NS
European Commission
EU Cosmetic Ingredient Database (CosIng)
Ceramide NS Dilaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Bromo-2-Nitropropane-1,3-Diol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Ceramide NG
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Ceramide NS
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Bromo-2-nitropropane-1,3-diol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Kitty Litter Dermatitis from-Bromo-2-Nitropropane-1,3-Diol.
Sullenbarger JW, Hensley B, Travers JB
Skinmed, 2017
Dietary ceramide 2-aminoethylphosphonate, a marine sphingophosphonolipid, improves skin barrier function in hairless mice.
Tomonaga N, Manabe Y, Aida K, Sugawara T
Scientific reports, 2020
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR