murphyDisodium Phosphate
AKA: 7558-79-4, Sodium phosphate dibasic, Disodium hydrogen phosphate, Disodium hydrogenorthophosphate, Acetest, Dibasic, Dibasic sodium phosphate, Disodium acid phosphate, Disodium hydrogenphosphate
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Synthetic
Clean
OriginProduced from phosphoric acid and sodium compounds through neutralization reactions. Synthesized by combining sodium hydroxide or sodium carbonate with phosphoric acid.
Disodium hydrogenorthophosphate
Solubility greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Formula
HNa2O4P
Mol. Weight
141.96
CAS #
7558-79-4, 7782-85-6
Form
Powder
State
Sodium phosphate, dibasic appears as a colorless to white crystalline solid. Soluble in water. The primary hazard is the threat to the environment. Immediate steps should be taken to limit spread to t
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Anticorrosive
Buffering
Antioxidant
Anti-Inflammatory
Boosts Collagen
Provides scent
Prevents product degradation
Maintains optimal pH
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory1 listing →
🛡️Safety-assessed2 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions mild to moderate (CIR 710)
Mixed Eye Irritation Results
2 studies / 1 irritating / 1 mixed / reactions minimal (CIR 710)
Concentration Guide
Leave-on0.000054–1.2%
Rinse-off0.000055–2.9%
0%50%100%
CIR reported use · 2015 survey
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR