Hydroxypropyl Starch Phosphate

AKA: DIHYDROGEN PHOSPHATE
Synthetic
Synthetic
Clean
OriginDerived from plant starch sources, primarily corn, potato, or tapioca plants. Modified through hydroxypropylation and phosphorylation chemical reactions applied to the natural starch backbone.
Hydroxypropyl Starch Phosphate is a cosmetic ingredient. Rated low hazard by EWG.
Formula
H2O4P-
Mol. Weight
96.987
CAS #
53124-00-8, 39346-84-4, 113894-92-1
Form
Powder
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Functions
Buffering
Adds Body & Volume
Controls Viscosity
Adds volume
Controls product thickness
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
2 studies / 2 not sensitizing (CIR 836)
Mixed Skin Irritation Results
2 studies / 1 irritating / 1 not irritating / reactions mild (CIR 836)
Eye Irritant in Testing
1 study / 1 irritating / reactions mild (CIR 836)
Concentration Guide
CIR lists it as not reported to be in use.
CIR · report published 2026
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR