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Phospholipids
AKA “Lipids, Membrane lipids”
Skin Conditioning
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Ingredient Facts
Phospholipids
AKA: Membrane lipids
Skin Conditioning · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Plant Oil
Clean
Phospholipids
CAS #
123465-35-0
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Naturally occurring components of cell membranes used traditionally in fat-based skincare preparations. Modern cosmetics use them extensively as emulsifiers, conditioning agents, and delivery systems for active ingredients.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
3 Piece Classic Suncare Travel Set
COOLA
 →
Balance + Support Duo
Marie Veronique
 →
Original Liplux® Lip Balm Sunscreen
COOLA
 →
Tinted Liplux® Lip Balm Sunscreen
COOLA
 →
Lunar Bloom Retinal Serum
Ursa Major
 →
Royal Tulip Moisturizing Nectar
Bloom Effects
 →
Barrier Lipid Complex
Marie Veronique
 →
Barrier Restore Serum
Marie Veronique
 →
Everyday Coverage Tinted Sunscreen, SPF 30
Credo Beauty
 →
Everyday Coverage Tinted Sunscreen SPF 30
Marie Veronique
 →
Gentle Retinol Night Serum
Marie Veronique
 →
Supernutrient Firming Facial
Marie Veronique
 →
The Body Brush
Credo Beauty
 →
The Body Tool
Credo Beauty
 →
Peptide Glow Hydrating Lip Treatment Refill
Credo Beauty
 →
Alpine Rich Cream
Ursa Major
 →
Peptide Glow Hydrating Lip Treatment
SOSHE Beauty
 →
Suncare Travel Essentials Set
COOLA
 →
Travel Fundamentals
Odacité
 →
Deposition of plant lipids after single application of a lip care product determined by confocal raman spectroscopy, corneometry and transepidermal wa
Bielfeldt S, Blaak J, Laing S, Schleißinger M, Theiss C et al.
International journal of cosmetic science, 2019
→
Two ceramide subfractions detectable in Cer(AS) position by HPTLC in skin surface lipids of non-lesional skin of atopic eczema.
Bleck O, Abeck D, Ring J, Hoppe U, Vietzke JP et al.
The Journal of investigative dermatology, 1999
→
Quantitative lipidomics profiling of skin surface lipids and skin barrier function evaluation in patients with acne vulgaris.
Cheng Y, Sun Q, Gao J, Liu Q, Tian H et al.
Archives of dermatological research, 2025
→
Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydro
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Glycine Soja (Soybean) Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycolipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hydrolyzed Phospholipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Phospholipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Placental Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Triticum Aestivum (Wheat) Flour Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Triticum Vulgare (Wheat) Bran Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Triticum Vulgare (Wheat) Flour Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycolipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Phospholipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Triticum Vulgare (Wheat) Flour Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Mitigation of retinol-induced skin irritation by physiologic lipids: Evidence from patch testing.
Fang Y, Ying Y, Xiaolan W, Lin S, Chenlan X et al.
Journal of cosmetic dermatology, 2024
→
Detection of fatty acid ethyl esters in skin surface lipids as biomarkers of ethanol consumption in alcoholics, social drinkers, light drinkers, and t
González-Illán F, Ojeda-Torres G, Díaz-Vázquez LM, Rosario O
Journal of analytical toxicology, 2011
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Cutaneous Permeation of a Percutaneously Applied Glucocorticoid Using Plant-Based Anionic Phospholipids in Hydrogenated Vegetable Oil: A Preliminary S
Greiner JV, Bhargava HN, Glonek T, Korb DR, Lindsay ME et al.
Medicina (Kaunas, Lithuania), 2022
→
Interaction between Sophorolipids and β-glucan in Aqueous...
Hiroaki Kaga, Masanori Orita, Koji Endo, Masaaki Akamatsu, Kenichi Sakai, Hideki Sakai
Journal of oleo science, 2024
→
Interaction between Sophorolipids and β-glucan in Aqueous...
Hiroaki Kaga, Masanori Orita, Koji Endo, Masaaki Akamatsu, Kenichi Sakai, Hideki Sakai
Journal of oleo science, 2024
→
Macrocystis pyrifera Lipids Reduce Cytokine-Induced Pro-Inflammatory Signalling and Barrier Dysfunction in Human Keratinocyte Models.
Kok JML, Dowd GC, Cabral JD, Wise LM
International journal of molecular sciences, 2023
→
Macrocystis pyrifera Lipids Reduce Cytokine-Induced Pro-Inflammatory Signalling and Barrier Dysfunction in Human Keratinocyte Models.
Kok JML, Dowd GC, Cabral JD, Wise LM
International journal of molecular sciences, 2023
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Final report on the safety assessment of human placental protein, hydrolyzed human placental protein, human placental enzymes, human placental lipids,
Nair B, Elmore AR, Cosmetic Ingredient Review Expert panel
International journal of toxicology, 2002
→
Synthesis of specific deuterated derivatives of the long chained stratum corneum lipids [EOS] and [EOP] and characterization using neutron scattering.
Sonnenberger S, Eichner A, Schmitt T, Hauß T, Lange S et al.
Journal of labelled compounds & radiopharmaceuticals, 2017
→
Emerging Lipids from Arecaceae Palm Fruits in Brazil.
Teixeira GL, Ibañez E, Block JM
Molecules (Basel, Switzerland), 2022
→
Comprehensive Extraction and Biological Activities of Mycosporine-like Amino Acids and Glyceroglycolipids Extracts from Two Macroalgae Ecklonia kurome
Wei X, Hu X, Li T, Li Y, Yu Y et al.
Foods (Basel, Switzerland), 2025
→
Lipids and the Permeability and Antimicrobial Barriers of the Skin.
Wertz PW
Journal of lipids, 2018
→
Verified Jun 2026
Data: CosIng · EWG · CIR