murphySodium Dehydroacetate
AKA: Harven, DHA-sodium, Prevan, New Side S 01, Dehydroacetic acid, Sodium salt, DHA-S, Sodium Dehydroacetic Acid, Sodium 3-acetyl-6-methyl-2, 4-pyrandione, Kyselina dehydroacetova sodna sul
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Synthetic
Skin Conditioner
Synthetic
Clean
OriginDerived from dehydroacetic acid, a synthetic organic compound belonging to the acetic acid derivative family. Synthesized through acetylation and subsequent sodium salt formation of dehydroacetic acid precursors.
Sodium dehydroacetate is a white powder. Used as a fungicide, plasticizer, toothpaste, preservative in food.
Solubility Soluble (NTP, 1992)
Formula
C8H7NaO4
Mol. Weight
190.13
CAS #
4418-26-2
State
Sodium dehydroacetate is a white powder. Used as a fungicide, plasticizer, toothpaste, preservative in food.
Skin Types
●all-skin-types
Best For
General
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Preserves Formula
Prevents microbial growth
The paper trail
🔬Peer-reviewed1 paper →
⚖️Regulatory0 listings
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
2
CIR
Safe as used
Pregnancy
—
CIR Safety Findings
Not a Sensitizer
4 studies / 4 not sensitizing (CIR 197)
Not Phototoxic
Human test and Product formulation test found no phototoxicity in the CIR safety assessment (CIR 197)
Mixed Eye Irritation Results
3 studies / 1 irritating / 2 not irritating / reactions minimal (CIR 197)
Mixed Skin Irritation Results
13 studies / 4 irritating / 5 mixed / 4 not irritating / reactions minimal to moderate (CIR 197)
Concentration Guide
Leave-on0.000005–0.6%
Rinse-off0.00003–0.2%
0%50%100%
Reg. limit 0.6%
CIR reported use · 2023 survey
EU regulatory limit: 0.6%. Source: EU Cosmetics Regulation (EC) 1223/2009, Annex V (Preservatives), Entry 13.
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR