Theobromine

AKA: 83-67-0, 3, 7-Dimethylxanthine, Diurobromine, Theosalvose, Santheose, Teobromin, Theostene, Thesal, 7-Dimethyl-3, 7-dihydro-1H-purine-2, 6-dione
Synthetic
Skin Conditioner
Clean
1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-
Solubility less than 1 mg/mL at 64 °F (NTP, 1992)
Formula
C7H8N4O2
Mol. Weight
180.16
CAS #
83-67-0
Form
Powder
State
Theobromine is an odorless white crystalline powder. Bitter taste. pH (saturated solution in water): 5.5-7. (NTP, 1992)
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Alkaloid compound naturally present in cacao beans, used in Mesoamerican cultures for centuries for stimulation and ritualistic purposes. Modern cosmetic use for its potential anti-inflammatory and circulation-boosting properties stems from traditional cacao applications.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Skin Types
all-skin-types
Best For
Dullness
Pregnancy & Breastfeeding Safe
Caution
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing
🛡️Safety-assessed3 reviews
Counts, not a verdict. A listing isn't a study. The trail, you decide.
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR