murphyTheobromine
AKA: 83-67-0, 3, 7-Dimethylxanthine, Diurobromine, Theosalvose, Santheose, Teobromin, Theostene, Thesal, 7-Dimethyl-3, 7-dihydro-1H-purine-2, 6-dione
Synthetic
Skin Conditioner
Clean
OriginTheobromine is a naturally occurring alkaloid compound found in cocoa beans and the Theobroma cacao plant. It is synthesized through chemical extraction and purification from cocoa solids or produced via total chemical synthesis from precursor compounds.
1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-
Solubility less than 1 mg/mL at 64 °F (NTP, 1992)
Formula
C7H8N4O2
Mol. Weight
180.16
CAS #
83-67-0
Form
Powder
State
Theobromine is an odorless white crystalline powder. Bitter taste. pH (saturated solution in water): 5.5-7. (NTP, 1992)
Skin Types
●all-skin-types
Best For
Dullness
Pregnancy & Breastfeeding Safe
Caution
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
The paper trail
🔬Peer-reviewednone on file
⚖️Regulatory1 listing →
🛡️Safety-assessed3 reviews →
Counts, not a verdict. A listing isn't a study. The trail, you decide.
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Mixed Skin Irritation Results (CIR report on the ingredient group)
CIR report statement covering this group of ingredients / not tested individually (CIR 773)
Concentration Guide
Leave-on0.0025%
Rinse-off0.00002%
0%50%100%
CIR reported use · report published 2024
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR