Tocopherol, Mixed

Tocopherol, Mixed molecular structure
molecular structure · PubChem
AKA: Vitamin E, Mixed Tocopherols, D-alpha-Tocopherol
Synthetic
Antioxidant
Skin Conditioner
Not Clean
OriginTypically derived from soybean, sunflower, or rapeseed oils as starting materials. Produced through molecular distillation and blending of naturally occurring tocopherol isomers.
Tocopherol, Mixed is a cosmetic ingredient.
CAS #
54-28-4 (gamma)
Form
Liquid
Skin Types
●all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Neutralizes free radicals
Prevents moisture loss
Vitamin E Nicotinate.
Duncan KR, Suzuki YJ
Antioxidants (Basel, Switzerland), 2017
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Vitamin E Nicotinate.
Duncan KR, Suzuki YJ
Antioxidants (Basel, Switzerland), 2017
→
Vitamin E Nicotinate.
Duncan KR, Suzuki YJ
Antioxidants (Basel, Switzerland), 2017
→
Instrumental evaluation of anti-aging effects of cosmetic formulations containing palmitoyl peptides, Silybum marianum seed oil, vitamin E and other f
Hahn HJ, Jung HJ, Schrammek-Drusios MC, Lee SN, Kim JH et al.
Experimental and therapeutic medicine, 2016
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Effect of talc and vitamin E TPGS on manufacturability, stability and release properties of trilaurin-based formulations for hot-melt coating.
Huynh VT, de Paiva Lacerda S, Espitalier F, Beyssac E, Ré MI
International journal of pharmaceutics, 2024
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Pharmacology and Pharmacokinetics of Vitamin E: Nanoformulations to Enhance Bioavailability.
Mohd Zaffarin AS, Ng SF, Ng MH, Hassan H, Alias E
International journal of nanomedicine, 2020
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Management of hot tar burn using vitamin e ointment containing petroleum and polyoxyethylene sorbitan.
Ng K, Dalen D, Rhine D
CJEM, 2013
→
Effects of antioxidant capacity-based dietary replacement of vitamin E with commercial products containing grape skin-green tea extracts or hydrolyzed
Simoni M, Danese T, Mezzasalma N, Goi A, Pitino R et al.
Frontiers in veterinary science, 2025
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Electrospun chitosan//ethylcellulose-vitamin E//ethylcellulose-curcumin tri-chamber eccentric Janus nanofibers for a joint antibacterial and antioxida
Zhang Z, Xia Y, Gong W, Zhou J, Yu DG et al.
International journal of biological macromolecules, 2024
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EWG
4
CIR
Safe
Pregnancy
Yes
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR